PHARMA PEELER CENTRIFUGE

The Horizontal Pharma Peeler is a batch type automatic / semi automatic filtering centrifuge. The axis of rotation of the basket in this centrifuge is horizontal. It is ideally suited for a clean room installation – ”through the wall” using a flexible membrane as required in pharmaceutical applications.

Technical Features:

Filling

The suspension that is to be separated is filled into the horizontal, overhung perforated basket at a pre-selected loading speed. As a result of the centrifugal force, the solid particles settle on the filter fabric on the basket shell. 

The solids are retained by the filter fabric, suspension fluid flows through the forming filter cake, including the filter fabric and leaves the perforated basket through bore-holes in the basket sleeve. 

During filling, the fluid level in the basket and the growth of the filter cake are controlled by sensors. Upon reaching the desired filter cake height the filling process is stopped automatically.

Intermediate spinning

Depending on the product, a filling process will be interrupted by intermediate spinning with increased speed, in order to free filling volume in the basket and continue the filling process. 

Depending on the filtration reaction of the product, intermediate spinning will be repeated several times. 

Washing the solids

As soon as the suspension fluid has been centrifuged, the washing the solids in the basket process is started. During this phase the washing fluid is evenly distributed via a suitable washing pipe (nozzle pipe or orifice-type sprayer) throughout the whole length of the basket. As a result of the centrifugal force, the washing fluid penetrates the filter cake, displaces the still sticking suspension fluid and leaves the basket in the same way as the suspension fluid during filling.

Spinning

In order to separate the fluid from the filter cake the basket is generally accelerated to the maximum allowable speed and kept constant at this speed. Kinetics of the spinning process depend on the solids and fluid parameters, the height of the filter cake and, naturally, the centrifugal force acting upon the fluid to be separated.

The residual humidity in the filter cake decreases over time under the constant  centrifugal force and asymptotically it approaches a theoretical limit.

Discharging

After hydro-extraction and with the basket rotating, the filter cake is peeled layer by layer by means of a discharge device, which consists of a knife box which can be rotated and moved in linear direction. 

The solids are then discharged via a suitable chute or a conveyor screw.

Residual heel removal

Generally, the solids are not completely removed, but a residual layer is left in the basket. It serves as a filtration accelerator for the next work cycle in order to obtain a filtrate that is as free from particles as possible.

However, this residual layer loses its permeability after several cycles and must be removed from time to time. This is done by separating the residual layer from the filter fabric by the use of a pressurized gas device that blows from the outside into the bore-holes in the basket shell. 

The residue is then transported out of the centrifuge via the discharge device.

Cleaning

Cleaning of the interior of the centrifuge is often required after every cycle or several cycles, in order to ensure a defined product separation between two following batches, or to prevent an infection. 

The inside of the centrifuge with all built-in devices can be completely cleaned with an integrated CIP cleaning system without the need to open the centrifuge.

Technical Details:

Advantages:

• Broad operational spectrum
• Highest standards regarding cGMP
• Fully automatic, validated CIP cleaning
• All components in the process chamber can be inspected
• Clean room installation (optional)
• Use of pharmaceuticals compliant materials and sealing materials
• Avoidance of potential sources of contamination